Gretchen E. Lyons
Biology
Senior Instructor
Office:
Room BBH 352G
Phone:
(773) 442-5720
Email:
g-lyons@neiu.edu
Office Hours:
Please email g-lyons@neiu.edu to arrange to meet or speak with Dr. Lyons.
Country:
United States
Expertise
Tumor Immunology
Introduction to Biology (BIO 100)
The Changing Natural Environment (BIO 104)
Essential Skills for Biologists (BIO 150)
General Biology I (BIO 201)
General Genetics (BIO 303)
Research Interests
Tumor Immunology
Education
Ph.D. in Molecular Biology from Loyola University Chicago (Stritch School of Medicine) and University of Chicago
B.S. in Biology from Boston College
Selected Publications
Spear TT, Riley TP, Lyons GE, Callender GG, Roszkowski JJ, Wang Y, Simms PE, Scurti GM, Foley KC, Murray DC, Hellman LM, McMahan RH, Iwashima M, Garrett-Mayer E, Rosen HR, Baker BM, Nishimura MI. Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability.J Leukoc Biol. 2016 Sep;100(3):545-57.
Zloza A, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O’Sullivan JA, Varanasi V, et al. NKGD2 signalling on CD8+ T cells represses T-bet and rescues CD4- unhelped CD8 + T cell memory recall but not effector responses. Nature Medicine. 2012 Feb 26; 18(3):422-8.
Zloza A, Lyons GE, Chlewicki LK, Kohlhapp FJ, O'Sullivan JA, Lacek AT, Moore TV, Jagoda MC, Kumar V, Guevara-Patiño JA. Engagement of NK receptor NKG2D, but not 2B4, results in self reactive CD8+ T cells and autoimmune vitiligo. Autoimmunity. 2011 Dec; 44(8):599-606.
Zloza A, Jagoda MC, Lyons GE, Graves MC, Kohlhapp FJ, O'Sullivan JA, Lacek AT, Nishimura MI, Guevara-Patiño JA. CD8 co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-β (TGF-β)-mediated suppression. Cancer Immunol Immunother. 2011 Feb; 60(2):291-7.
Lyons, GE, McCracken J, O’Sullivan J, Guevara-Patino J. RAE1-e Signaling Rescues “Helpless” CD8+ T cell Memory Responses. Journal of Exp. Medicine. January, 2011.